The Truth about the Drug Companies By Marcia Angell Essays

The Truth about the Drug Companies By Marcia Angell Essays The Truth about the Drug Companies By Marcia Angell Paper The Truth about the Drug Companies By Marcia Angell Paper Americans every day are subjected to a bombardment of advertising by various pharmaceutical companies. The advertisement is mixed in with different pitches for a drug showing beautiful people who are enjoying in the outdoors is the main message. Coming down to the essential and this is what is said: Prescription drugs are very costly but that shows how precious they are. The Research and Development costs are huge and companies need to cover them in some way. Research based companies tend to turn out a stream of innovative medicines which enhance its quality, averts more expensive medical care and extends life. People are the beneficiaries of the achievement of the American free enterprise system so we should all be grateful, and stop whining and pay for the drug. The industry says that you get what you pay for. Prescription drugs cost are very much high and rising fast. Americans spend around $200 billion a year on prescription drugs and the figure is growing at a rate of 12% a year. The fastest growing parts of a health care bill are Drugs which are also rising at a fast rate. The increase spending on drugs show that people are taking a lot more drugs than they used to. The prices of those drugs are frequently increased sometimes several times a year. Before its copyright ran out, the price of Schering Plough’s allergy pill, Claritin was increase about twelve times in a time span of five years for a total increase of more than fifty percent. Poor people are not the only one having a problem paying for the prescription drugs. Health care is shrinking due to the struggling economy. Employers want workers to pay more for the cost themselves and many organizations are decreasing health benefits. As the costs of prescription drugs are increasing so fast, payers are eager to get out from under them and shifting the cost to the individuals. The end result is that more and more people pay a larger fraction of their drug bills out of their own pocket and that is way too costly. Many people cannot pay so much. They tend to trade of drugs against food or home heating. Some people take them less often than it is prescribed or share them with a family member. Some who are too embarrassed to admit that they cannot afford to pay leave the doctors office with prescription in their hand and not getting it filled. These patients go without the treatment needed and sometimes their doctors wrongly conclude that the drugs they were given haven’t worked prescribed by other which complicates the problem. Elderly people get hurt the most. When Medicare was ratified in 1965, people took less prescription drugs. No one thought it is important to include an out patient prescription drug advantage in the program. Senior citizens could also buy the drugs which they needed. Around two thirds of the elderly people had additional insurance which covered prescription drugs but that percentage is decreasing as insurers and employers decided that they suffer from it. A medical reform bill was passed by Congress at the end of 2003 which included a prescription drug benefit which was to begin in 2006, but its benefits are insufficient to being with and will rapidly be taken over by administrative costs and rising prices. For apparent reason elderly people need more drugs than younger one. In 2001, around one in four elderly people reported that they do not take regular does or do not fill prescription because of the costs. The frailest are least likely to have a supplementary insurance. An average cost of $1500 a year for a drug, a person without an additional insurance who take different prescription drugs would need to spend around $9000 out of his own pocket. Not many people have such deep pockets. In one of the more wicked practices of the pharmaceutical practices, prices are higher for the people who mostly need the drug and can least afford them. The pharmaceutical industry charges the Medicare recipients more than its favored customers such as Veterans affairs system or HMO’s as the latter buy the drugs in a bulk quantity and they can bargain for rebates or discounts. People who do not have insurance have any bargaining power and therefore pay the high prices. In the last two years, people have started resisting to the increasing prices and other practices of the industry. Because of this resistance, drug companies are now covering us with different public relations messages which include the magic words like innovation, research and American. While the expression is inspiring, it has little to do with reality. Research and Development is a small part of a company’s budget. Year after year for over twenty years this industry has been the most profitable in the United States. The price drug companies’ charges have a minute relationship to the cost of making drugs and can cut them with coming close to threatening Research and Development. Secondly pharmaceutical industry is not innovative. It is hard to believe only a few important drugs have been brought into the market in the past years and they were mostly based on tax payer funded research at small biotechnology companies, National institute of Health or at academic institutions. Majority of the new drugs are not new but variations of older drugs. These are known as me too drugs. The main idea is to have a share of the lucrative market by manufacturing something similar to a top selling drug. For example there are six drugs in the market, Mevacor, Zecor, Pravachol, Lipitor, Crestor and Lescol which controls cholesterol and copies of the first. Finally the industry is hardly a model of the American free enterprise. It is free to decide which drugs to produce and it is totally free to price them as high as the public can bear and are totally dependent on the government granted monopoly in the form of Food and Drug administration’s approved marketing rights. It is not particularly innovative in making new drugs but it is aggressive and highly innovative. As America is a main profit center, it is good public relations for the companies to show themselves as American they are or not. It is true that some European companies are starting their R D operation in America. They say that the main reason behind it is that United States does not regulate prices as much of the world does. Drugs which are less profitable and which fight against tuberculosis and malaria tend to receive less attention. George Bush who is friendly to the big pharmaceutical industries refused to allow the promised $15 billion in funds allotted for HIV treatment in the Third world to be spent on common drugs. Among the many tricks exposed are the huge pharmaceuticals use of contract research organizations to apply excessive influence on clinical research and its sinister seduction of doctors. Drug companies in 2001 gave doctors nearly $11 billion worth of free samples. Along with that they gave other incentives to the doctors. In the final chapter of the book, there are seven important reforms, chief of which is for the Food and Drug Administration to compare new drugs with old drugs to see if there are additional benefits. The main goal of Angell is that people can get good drugs at a reasonable price and this require pressure from the public so that the government may take necessary action against the pharmaceutical companies. She performs an important public service in focusing on the drug companies and their dishonesty. The improvement of Pharmaceutical companies start with the outcry of the public against the abuses she showed in the book. She says that doctors should stand by their patients and not their pockets. Personal Opinion There is a significant problem in the United States about the financial conflict of interest in the clinical drug trials. It tends to affect millions of people those who are subjects in drug trials and those who use the drugs. The drug companies frequently control the date which is collected in the drug trials. The university scientists even are not provided with the whole data. Big companies tend to publish data which is favorable to their product which holding back the unfavorable data. In the case of Dr James O Kahn who published a journal article in which he concluded that a vaccine for AIDS did not help the patients. Dr Kahn was not given the data he required. But still he managed to publish the study. The company started a legal action against Dr Kahn and its employer, the University of California worth $ 7 Million. If such things happen very few researchers will have the courage to stand up to the companies. Pharmaceutical companies design their own studies to make their drug look more effective than they really are. Patients tend to suffer from the studies that offer incomplete or false information including the information about the doctors financial relations to the company. There is a need for improvement with the clinical drug trial process where there must be some other party testing the drugs. Scientists outside the company should have the final say on the drug trials. All the data should be available to the project investigators and to the public, press and who ever needs it. All financial relations to the companies should be made public. People need more information and more safety. The time is right for the nation’s medical centers, medical journals, FDA (food and drug administration), universities, medical journals and National institute of Health to come together and tell lawmakers to take back the rules under which the medical products are approved and tested. Bibliography The Truth about the Drug Companies` by Marcia Angell Publisher Random House; 1 edition (August 24, 2004)

Critically Review the Blossoming Garden Centre case study Essay

Critically Review the Blossoming Garden Centre case study - Essay Example This has called for the emphasis on training and development of the workforce too. Consequently organizations have been observed to be making huge investments in conducting training needs analysis, developing training modules, and delivering the same to its human capital. Organizations constantly creating new knowledge and imparting the same through effective training and development to employees are seen to be providing better services and products to customers than others. Constant learning and development has become the key for success of the organizations (Vemic, 2007, p.1). This project seeks to bring forth the present HR conditions in Blossoming Garden City. For this purpose it conducts an evaluation of the organizations’ learning and development issues in the organization. The first issue which is observed is that the organization easily finds staff for itself but lacks the desirable skills or the willingness of these staff to get hands on experience with customers. The organization primarily faces difficulty in finding executives at the management and supervisory level. It is also expected that restructuring the management responsibility would be a difficult issue when Gordon would retire, who has been the Managing Director of the company since 1985. Moreover the nature of the business reveals that staffs need to be in constant touch with customers. This demands the right kind of customer skills which in turn demands adequate training on the skills. Training is considered to be an ongoing process in the organization, however, inadequacy of a formal training structure has been observed. Identification of Needs The report focuses on the learning cycle presented by Kolb, in terms of identifying the training needs, planning, delivering and evaluating the elements of learning and development. According to Kolb, every individual needs and responds to the stimulus of various types of learning styles to certain extent or the other. Depending on the best learning styles that fit the employees’ organizations set their learning strategies and preferences (Harrison, 2005, p.83). The following diagram provides Kolb’s learning cycle (Please refer Appendix 1). Researchers and practitioners have realized the requirement for training needs analysis as being an integral part of the organizations. In order to utilize resources successfully, it is important for organizations to determine the exact scope, location and magnitude of the training needs. Researchers have highlighted on the fact that there exists no justification of investments in training programs if it does not end up enhancing or improving the efficiency of the workforce of the organization (Moore & Dutton, 1978). Training needs analysis accounts for the very first step in the cyclical process of the overall education and training strategy staffs in organizations. According to the views of Gould, Kelly & White & Chidgey, (2003), training needs analysis begins with t he systematic consultation of identification of learning needs of the staff which is consecutively followed by the program planning, delivery and evaluation of the training programs. Research was conducted on micro and macro level organization for evaluating their training needs and assessments. It was revealed that in spite of their limited and small scope, the micro level organiza

Describe a place or environment where you are perfectly content. What Personal Statement

Describe a place or environment where you are perfectly content. What do you do or experience there, and why is it meaningful to you - Personal Statement Example Oftentimes, when given the opportunity, I will take my horse out into the desert and just enjoy the peace and solitude that such an environment can provide. Whereas many individuals might see the desert as a formidable and barren landscape, the fact of the matter is that to me it is tranquil, serene and quite lovely. I find myself experiencing feelings of complete contendeness when I am in such an environment and free to let my thoughts wander about on many different topics. For everyone there is a place or a situation in which they feel most content; for me, it is the time I spend alone on my horse in the wilds of the desert. It should not be understood that the only calm and contented times that I spend are in solitude. Rather, my friends and family often accompany me as I embark on either a short few-hour trip or a long over-the-weekend ride. Sharing the experience in being able to be outdoors and away from all of the concerns and worries of work or school allows for this to be the single most contented time that I have spent during my life. Another reason that the time spent in horseback riding is oftentimes the most contented has to do with the fact that I am able to forget about my other concerns in life. Whereas driving somewhere is of course possible and sometimes easier, it does not allow me to quietly observe all different types of wildlife that I get to see while horseback riding. As compared to the drone of the engine in a car, the quiet gait of the horse has the ability to free my nerves, and therefore allows for a much more observant and natural means to behold available wildlife. The ability to rapidly learn the skills of horseback riding and master them in a relatively short period of time is perhaps one of the greatest reasons why this has become one of the activities in which I have been the most content. Further, as with any experience, the experience that the reader may have can vary

Better Off Alone Essay Example for Free

Better Off Alone Essay In the bible God’s greatest servant is Job; â€Å"This man was innocent, upright, and God-fearing, and kept himself apart from evil† (66). Job did everything God requested, and yet Job was maliciously tested by his creator. Throughout the story of Job there were several accounts of Job expressing his misery that resulted from God’s cruel tests of faith. Reading the story of Job I came up with the question of, would Job be happier without the weight of God’s continuous misperception and unannounced tests? Yaweh strikes Job with a â€Å"test† and murders his sons, daughters, and animals to see if Job will still love him. Perhaps God didn’t have faith in Job instead of visa versa. Yaweh causes Job to be miserable and want to kill himself; in no way is this enjoyable, or worth proceeding to worship a deity. If God were to tell Job he is the one who permitted all of these deeds, Job would no longer follow this deity. God is lying to get what he wants from Job, I don’t believe Job would still appreciate a God that goes against what he orates. It’s as if a wife had gone behind her devoted partners back and had a secret accomplice to pursue her other in a â€Å"test† of fidelity; If she were to tell him â€Å"I tested you, and had another female pursue you to see if you would stay loyal to me†, He would be mad and most likely leave her for lack of trust. Just as Job should leave his â€Å"creator† in the dark as nothing and move on to be happy, instead of constantly trying to please a God that is never satisfied. Job is â€Å"innocent† and â€Å"kept himself apart from evil† (66) and he was also tested with God’s sinful acts of murder and pain. Job was more than true to God, he showed this by even filling his own son’s faithful void; â€Å"Job would send to purify them, rising early in the morning to offer whole burnt offerings, one for each† (66). First off Job was this great of a servant so therefor Job should have been treated better and shouldn’t have been tested. This didn’t happen; but if Job was questioned because he is known as God’s ultimate servant and he had to live up to high standards then feasibly, Job wouldn’t have to deal with an untrusting God if he never submitted. Yaweh speaks with the Accuser and even points out himself that Job is â€Å"like no one on earth†; â€Å"Have you taken note of my servant Job, for there is no one like him on earth: Innocent, upright, and God-fearing and kept himself apart from evil† (66). This is a repetitive sentence through the first section of the story; making a statement that Job has all of these reliable qualities for his God. Job is pious; even Yaweh speaks of this, right before he causes Job an enormous amount of pain. When Yaweh and the Accuser speak of challenging Job’s allegiance, Yaweh tells the Accuser â€Å"Everything he has is in your power, but do not harm his person† (67). Emotions are a part in one’s brain, and one’s brain is a part of the â€Å"person†. By killing his family and animals, this is creating the feeling of agony (harm) to his person. One can then notice God either doesn’t know what harm is or he is just so unpleasant he doesn’t care if he causes Job discomfort, he just wants to see the outcomes of such mischievous acts with Job’s irrevocable loyalty. This isn’t fair to Job, to be harmed for entertainment, what an unhappy life to live. In result of God’s first test of faith, Job unchanged, remains faithful. God figures, well that’s not enough, he then changes his statement to the Accuser and says â€Å"He is in your power, but see that you preserve his life† (67). Yaweh goes back on his words and then physically harms Job’s â€Å"person† and â€Å"smote(s) Job with sickening eruptions from the souls of his feet to the crown of his head† (67-68). Job wouldn’t need to prove devotion to God through anguish if he just had escaped from this unfortunate cruel God. The only reason Job is being chosen to be tested is because he is God’s ultimate servant. If he didn’t believe in God then he wouldn’t have been chosen because God would have already known he was not faithful. Nothing would happen to him if he said good bye to God because all of Job’s friends told him not to keep following God, and nothing cruel happened to them. Job would be happy not constantly being subjected by God’s insecurities. Just how miserable was Job? Job was enormously depressed which shows in this quote; â€Å"blot out the day when I was born† He wishes to not remember the day he was born, or wish it never happened. With his words of self-loathing it creates to the reader feelings of suicide and hate. It makes the reader feel almost apathetic towards Job, for not listening to his friends and also continuing to follow a horrendous god.

Neuropathology Of Downs Syndrome Essay -- Medical Disease Health Essa

Neuropathology Of Down's Syndrome Down’s syndrome is the most commonly identified cause of mental retardation occurring in 1 out of 700 live births. In addition to mental deficiency, characteristics of the disease include epicanthic folds of the eyes, flattened facial features, unusual palm creases, short stature, open mouth, protruding tongue and poor posture. A twenty-two to fifty fold increase in risk of the development of leukemia along with congenital heart defects in forty percent of these individuals is also seen. The increased level of purines often found can lead to mental retardation itself. Neurological impairment and immune system deficiencies make these individuals more susceptible to infection. Also noted are increased risk for cataract development and vision impairment due to defects in the lenses of the eyes. Evidence for the disease can be found as far back as the nineteenth century with many theories for the etiology of the disease. Early hypotheses include links to endocrine gland malfunction, tuberculosis, syphilis and "uterine exhaustion". The idea of uterine exhaustion was based on the observation that many children with Downs Syndrome (DS) tended to be the last born members of large families. This was later accounted for as mere coincidence. The first formal reference to the anomaly came in 1866 in England by a physician at the Earlewood Asylum noting the distinct physical characteristics of this group of individuals. In the 1930’s, Adrian Bleyer hypothesized that the condition was caused by a failure of the chromosomes to separate but could provide no proof for this since an accurate human chromosome count had not yet been obtained by anyone. The correct number of 46 chromosomes was obtained in Sw... ...rebrain Cholinergic and Pontine Catecholaminergic Nuclei in the Brain of Trisomy 16 Mouse, an Animal Model of Down’s Syndrome. Brain Res. Devop. Brain Res.:50(2), 251-264. LeMay, M. and N. Alvarez (1990) The Relationship Between Enlargements of the Temporal Horns of the Lateral Ventricles and Dementia in Aging Patients with Down’s Syndrome. Neuroradiology: 32 (2), 104-107. Patterson, D. (1987) The Causes of Down Syndrome. Scientific American: 255 (8), 52-60. Pearlson, G. D., et. al. (1990) Brain Atrophy in 18 Patients with Down Syndrome: a CT study. AJNR: 265, 811-816. Plioplys, A. (1987) Down’s Syndrome Precocious Neurofilament Antigen Expression. J. Neuroscien.: 79, 91-100. Sacks, B. and S. Smith (1989) People with Down’s Syndrome Can be Distinguished on the Basis of Cholinergic Dysfunction. J. Neurol. Neurosurg. Psychiatry: 52(11), 1294-1295. Neuropathology Of Down's Syndrome Essay -- Medical Disease Health Essa Neuropathology Of Down's Syndrome Down’s syndrome is the most commonly identified cause of mental retardation occurring in 1 out of 700 live births. In addition to mental deficiency, characteristics of the disease include epicanthic folds of the eyes, flattened facial features, unusual palm creases, short stature, open mouth, protruding tongue and poor posture. A twenty-two to fifty fold increase in risk of the development of leukemia along with congenital heart defects in forty percent of these individuals is also seen. The increased level of purines often found can lead to mental retardation itself. Neurological impairment and immune system deficiencies make these individuals more susceptible to infection. Also noted are increased risk for cataract development and vision impairment due to defects in the lenses of the eyes. Evidence for the disease can be found as far back as the nineteenth century with many theories for the etiology of the disease. Early hypotheses include links to endocrine gland malfunction, tuberculosis, syphilis and "uterine exhaustion". The idea of uterine exhaustion was based on the observation that many children with Downs Syndrome (DS) tended to be the last born members of large families. This was later accounted for as mere coincidence. The first formal reference to the anomaly came in 1866 in England by a physician at the Earlewood Asylum noting the distinct physical characteristics of this group of individuals. In the 1930’s, Adrian Bleyer hypothesized that the condition was caused by a failure of the chromosomes to separate but could provide no proof for this since an accurate human chromosome count had not yet been obtained by anyone. The correct number of 46 chromosomes was obtained in Sw... ...rebrain Cholinergic and Pontine Catecholaminergic Nuclei in the Brain of Trisomy 16 Mouse, an Animal Model of Down’s Syndrome. Brain Res. Devop. Brain Res.:50(2), 251-264. LeMay, M. and N. Alvarez (1990) The Relationship Between Enlargements of the Temporal Horns of the Lateral Ventricles and Dementia in Aging Patients with Down’s Syndrome. Neuroradiology: 32 (2), 104-107. Patterson, D. (1987) The Causes of Down Syndrome. Scientific American: 255 (8), 52-60. Pearlson, G. D., et. al. (1990) Brain Atrophy in 18 Patients with Down Syndrome: a CT study. AJNR: 265, 811-816. Plioplys, A. (1987) Down’s Syndrome Precocious Neurofilament Antigen Expression. J. Neuroscien.: 79, 91-100. Sacks, B. and S. Smith (1989) People with Down’s Syndrome Can be Distinguished on the Basis of Cholinergic Dysfunction. J. Neurol. Neurosurg. Psychiatry: 52(11), 1294-1295.

Should Cellphones Be Allowed in Class

Should Cell Phones Be Allowed In The Classroom? Personally, I think cell phones should be allowed in the classrooms as they can benefit students in many ways. Student’s listen to music on them, do research on them, and they benefit students with individual education plans. To start, cell phones should be allowed in the classroom, as student’s use them to listen to music. In addition, listening to music helps people concentrate on their learning as it avoids them from getting distracted at what is going on around them. Also, listening to music helps student’s deal with emotional problems, stress, etc.Therefore, students should be allowed to bring their cell phones to class. Next, I think students should be able to bring their cell phones to class considering it is helpful when it comes to them having to do research on something. Cell phones are helpful to students when it comes to doing research, as they can save what they researched on their phone and come back t o it later. Furthermore, cell phones are good when it comes to needing to do research as sometimes you could wait days to use the school computers, but if you have a cell phone with a data plan you can have all the research you want at the end of your finger tips.In conclusion, cell phones should be allowed in the class as they do benefit student’s when it comes to doing research. Finally, cell phones should be allowed in the classroom, as they can benefit students with individual education plans. For instance, cell phones can help benefit student’s with I. E. P’s because they have cameras on them which student’s can use to take pictures of their assignments who cannot write, student’s can also type up their work and print it, and lastly if they have a hard time when it comes to reading something they can use applications like Kurzweil or dragon and have it audio read to them.To summarize, I think cell phones should be allowed in class, as they are a very useful device when it comes down to students with individual education plans learning. To conclude, students should have the privilege of bringing their cell phones to class, as they can help benefit students in their learning in several ways. For example, they can be used as a calculator for math. To wrap it up, students should be able to bring their mobile devices to class, as they can benefit students in so many ways.

Chaucers Canterbury Tales Essay - The Powerful Wife of Bath

The Powerful Wife of Bath In Geoffrey Chacers The Canterbury Tales we are introduced to 29 people who are going on a pilgrimage to St. Thomas a Becket in Canterbury. Each person is represented to fit a unique type of behavior as shown by people during the medieval ages. My attention was drawn to the Wife of Bath through which Chaucer notes the gender inequalities. Predominantly, women could either choose to marry and become a childbearing wife or go into a religious order. Women were seen as property. Women during this period of time, had limited choices when it came to societal roles. The Wife of Bath exonerates the accepted roles of society, reflecting womens attempt to gain†¦show more content†¦1-2) She is confident about her knowledge of love, virginity and marriage (after all she has been married five times). Just as men use the bible to justify womens oppression, so did the Wife of Bath. She states that double standards for women are deeply rooted in society. The Wife of Bath addressed and dispels the justification for multiple marriages through biblical figures and stories. I woot wel Abraham was an holy man, And Jacob eek, as fer as evere I can, And eech of hem hadde wives mo than two, And many another holy man also (p.118, ll. 61-64) The Wife of Bath relied on the bible to justify her unaccepted views, but when the bible did not favor her views she simply disregarded it. The Wife of Bath is a widow and therefore it is assumed that she would dress rather conservatively. This is not the case for the Wife of Bath. Her clothing is quite flamboyant with scarlet red leggings, soft new shoes, broad hat, and spurs on her feet. She is obviously not dressed in a typical manner or style of other women in her time (Hallissy 42). She disapproved of her husbands attempts to inflict control upon her. SheShow MoreRelated Powerful Satire in Chaucers Canterbury Tales Essay3466 Words   |  14 PagesPowerful Satire in The Canterbury Tales If one theme can be considered overriding or defining throughout Medieval European society, it would most likely be the concept of social class structure. During this early historical period in Europe, most of society was divided into three classes or estates: the workers, the nobles, and the clerics. By Chaucers time, however, the powerful estate structure had begun to wear down. Weaknesses in the system became apparent, as many people, such as ChaucerRead MoreEssay about Chaucers Wife of Bath2474 Words   |  10 PagesChaucers Wife of Bath Before beginning any discussion on Chaucer’s Wife of Bath, one must first recognize that, as critic Elaine Treharne writes, â€Å"Critical response to the Wife of Bath has been as diverse as it has been emotive† (2). Some critics love the Wife of Bath and her controversial prologue, proclaiming that she is a woman of strength and powerful words; others hate her and cover the eyes of younger girls, determined that Wife of Bath is instead a role model of what women should notRead MoreThe Fight For Gender Equality Essay1357 Words   |  6 Pagesargued for gender equality. Now, this essay won t focus on every aspect of gender equality by every single influential person, but it will zoom in on certain notable literary figures that incorporated progressive views within their work. All things considered, the essay will analyze the role of women within Chaucer and Shakespeare s literary work while keeping the historical, Middle Ages and Renaissance, time periods in mind. More Specifically, â€Å"The Wife of Bath’s Prologue,† by Chaucer and â€Å"AsRead MoreWomen s Unequal Portrayal, And The Struggle For Identity Of Female Writers1777 Words   |  8 PagesIn this essay I will examine the ideas behind women’s unequal portrayal, and the struggle for identity of female writers. Before recently, most published writers were male, so representation was obviously one-sided. Literacy in the ancient worlds was limited anyway, and few that could write were female. Oral culture is undervalued, though, because folktales were predominantly passed down by women. Religion played a huge part in early misrepresentation. Plato laid the philosophical foundations forRead MoreA Picatrix Miscellany52019 Words   |  209 PagesYou also ought to place [the Moon] in this Mansion for all images you intend to fashion that you might travel on the road and be returned home safely. They also account this sign [Mansion] good for the creation of discord and enmity between a man and wife, and for the creation of enmity between two friends. The foundation of all acts for good purposes is an observation, namely to see whether or not the Moon is in a good condition, and is safe from [aspect with] Saturn, Mars and from combustion with